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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f6aac660f33928dec3863459a15aa3f88ebbbd6a7a8a1ada237a5b8cb55461b' 
  AND token = 'EVWpdprZczzgZXHU3/9IBsfV4mjZH142np3OaBjvFQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}