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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf35e1910c19357ef8e5a6403fdf20dfb87a3f90906af3f30e7543d787aacf8' 
  AND token = 'wi2l58WpgZ2zDCv1VymMehMGl1SGGnSO2n3Xrh+uFtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}