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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16dc3a5683b0e1e90fb1fe270109f3e84b15a975a16159f8f5c92f2973cc9b90' 
  AND token = 'UbcGMPHRRP+OhZz1MEv3EU2PxkUmRmsxMla+jcYGHOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}