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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23b43978e066813e9ecb8f2e2f59b767be3613b6f826fd70bae92f5a16fd7af2' 
  AND token = 'EsCvSommuulSZsuutYordTN9zeUssXDEuxCD/OXkNLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}