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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '323d4c9302673a0d6f78c5f0d7d1bdb27816e86c49f27c4496502605f0547982' 
  AND token = 'UtQHdd54dgtW5OgpcZTZQtN5HwMGgPj6+kj7uxR95HA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}