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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f70007483eabcfa249aa62e62d03d850d753e01e2e74708dddd0be2ec0a7d76a' 
  AND token = 'V9jQipWtHexOn/Zf8Qx1KZjLJUI3iHmxsg8OF1m0zNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}