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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6de5fca53e5bbb2e015c3c17225664c7cf6da04872e7772f38f26afced8b27' 
  AND token = 'tGJYVgZQ24nNYtNiiFLKIa/736+ntPHyjFnTbBDbJuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}