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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a84739e34f59e47c2abf7d1295eb2d5276ba0a3a180b5390d8ab51722aecac2' 
  AND token = 'VCQuJVq+rHiR3ATYR1hNBf0dyc8iNm1eKOdMmmFHpx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}