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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4579d5f5239326e73850952be15ee1dce405b07937112e9478751a16f5e8d5d5' 
  AND token = 'HE7ChKOStqZ2pR7K5W1vEsPZOFX/ky16BzR1pl9kaR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}