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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7df3de94e81f91205b85f6987331392264e99775fcce5dc492d45feab38133fa' 
  AND token = 'e/szYQ9s8W5hzx4rdBPKXxrhSQbVLc0sMU7n6GmUGmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}