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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efeeb2e6fde45f5561700d30274e3b920675605d78f11722af94a0df4c409760' 
  AND token = 'B4JqmDYZIY0gK2bBgVZRO91FoKzy1lNEacLcNcRWoKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}