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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c3f41830aff58c1ecf8916674e3fd63c8b1e38948cd2ec761609d2378efc191' 
  AND token = 'oohCP+iM1YIFOm9BXPYL4n/k6KM6d9lHmiKj+Wra4ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}