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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0361ed45a5d307dfa48a3162610f6717e3bae86a52fbf79d24980914035bfc0' 
  AND token = 'AxNVCRu2E2BAYG64eUOtW4uJ+WnXuIYg7Nq0HNMDCoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}