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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4281fafef1c215b3626f128e7b6429c6389a19639f7ea7790bce15acff9efa25' 
  AND token = 'wq8OWQELCWJri0cCudhd4c1ssosuASAKuyRf4ZLWRFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}