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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497c1d8699ce970ae758a4ad99e5b2fb9fa5fc22a6aa56e40be72f15ed06c8a4' 
  AND token = 'FbPbV2Rbzy/Ao7372fyA8AIM2PPV9vLSjeTp0lLsLtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}