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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9583fd0453c9fa8b7896dcc6d88da00f3872f94083402623aaada9b38045181' 
  AND token = 'I7MES4/39H6cc2CTC7GevtKwU64DhoxtY6CUYWTud9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}