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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f74e1cec31fbc0ddaca0bfe59b1fba255bbfdd270bc85e360f74c236ef3f560' 
  AND token = 'knz+ZTh0BG5g+pAlVnVmB+CTRG2Z2EFL36JVqF3dmGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}