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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf1b99d283e8186ca6b587808c69e8c929f3a6622d0d4395482f9db24d34402' 
  AND token = '2w4eZsQ6Z2Q15dOFZ+KRnSVvtF1Nwhjkt78CwlteF5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}