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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a7bf232c483a58d7de75d0067687e435148823b067a10035ef74842ffd50101' 
  AND token = 'ApGzAs3HwN/q9PUzqqQDcq7RPoY5+j6s/2Xz1Y7XcfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}