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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497259fef94258374cbd0baddc5f402cc950d5b658b58e7874692d422cb4d9fb' 
  AND token = 'yZyapuJt19d7zikp71LUamTYbc6XZyG42w95VdEVe/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}