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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc78980bf01062c16d02e701955bd6e0fb852a4fb3fece05ceee39c8ede85513' 
  AND token = 'PZ4dQT0vegxRAGnfzY3J7cypcTxccX1dCO/hDZVBPhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}