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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4f7ac385b762436086d8a4139c6c7ec0013cb37acdff11885215c7fa1aff69' 
  AND token = 'Ipa6hYYik58B3VaAW3UWp45AYCuZd4w9MkD/xShQg9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}