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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667794266e90af4aa5e63b942c0dcf4d07b964e630ad0b914bc2436d616448ec' 
  AND token = '8pK1IdEuTwql5aLvTjihGYl1Fmpvkv7lPjyIlW0GOB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}