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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e95d97b5f2d2d9057c81771d418f18982c8e4b452801b2399ec049dcb86f6f' 
  AND token = '5HOl+CFiUsdwSSi4bC0s17rZsyeTQnDVFuaMkG/2bVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}