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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee37b89b787acaf62b2ba3484ed289dbce85d2e8bdaaa21bb1bcdd3adc9d98b' 
  AND token = 'nk2MTOqnx6yuMOn4SX/yGuVp075lJfpMZK6tH9EHmIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}