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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ea19da8e056aeb4d0a0b8d7e89faa37d23cdbbd813c4c7a2f6e49e33e4566e' 
  AND token = 'vcAkrekut9/Si31Md2rkVXkg4OiVJdILscU1UD0/Bc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}