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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363a62d3b92d866e2459f4fa4a562fece0deef3dd59e35d3d9d4bf14fd0c6c36' 
  AND token = 'HUHuw9d+bJpFR+XPfelja9t9vTShZ6vXQouEntvCmeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}