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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be1117db6f0f8b7b6c7dbca47e4b96d6f7757bfb7437b567299e42ce327d38d2' 
  AND token = 'BCZBr2+oVU+yaBSk8sFCDdcXp8rrqN4Q3NRPjgdJmuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}