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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c42238e0d1a6d03c295d25532fca5b236a32ab236819463a9e0cc98de9fc1ad' 
  AND token = 'XSVQjN0e9IRobfaNPNuSqMrHW0UmJXiT9MMBkiaVfx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}