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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ab976178d310429bfb7acad3b381e5cf4ed15e7320be2b47d7b08bdda1aa673' 
  AND token = 'LI1oZ0L8jX9tzRPnMimFjCWdMpiyRFvSe/de6U1tJTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}