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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db6bfae1acf951f3d21135e59047924e8bf734cc16e6f70428c5cc5413d06a28' 
  AND token = '8Dxniz0KgtmtsKMJFfppyY+zIEi/eQYyFBWfca65sZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}