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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '127cff9d8caa514ef66a83ad8c5bac829c588572e8580260c74e42e5c1a06a0f' 
  AND token = 'QsrxCofX+2Z4nomng1sIQQmP88TeJkIMA+4Ut15qexY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}