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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac4d5e57bcb84e30ec85126e75bf5fd76fdb28ec2e39848dac23a949d09db4ed' 
  AND token = 'reejn2R/Fe/ZTP8B2wLNV+9VuNoF4P985WBSlHmBXxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}