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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46a08a524e206c2506720e8f07790bb1c31613bbbcfb5f5ad9e296a274a604d' 
  AND token = '7vdKnhIMrnrT4vcTW29nfLxl5Oft8/3P7Nm0aGTsHA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}