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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed710ab70db971494029ba3ff26eeef3fde600d9e58aedf7acbe6539f589c012' 
  AND token = 'j6mzDEgav1vuFoOFTYkt0Qh3QA2bhp4xDJslDkOvR0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}