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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196b0a66a14783b5f384905d6f5e574a8056018d4c38dab8bb52324f8bf2e834' 
  AND token = 'b8gxbu/n7x//N0Fkba649gmnWwugFJsEvcQntYfz6pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}