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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '432b33e502a22fead210578a23e722702006d4b07ece6469af1e6c50aa9ebc72' 
  AND token = 'BClppAwTkeiZ+etRh099WUfuBGx391Brrtb9WDMOyns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}