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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e793bc18efb5abff2903585611fb37ffffa767bb5254e6ed1f17c7b0e07b9120' 
  AND token = 'zrkcWJWTFTapO58+9ETWbUPgUsIsMrZoyWi79pjCNcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}