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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f7fd278e0d4a6ff748c0b7d554c37d3b77ae71e430cc5772391e789fc326f4' 
  AND token = 'mxk1frtIXfXurxov2/IuRRSC9Vq39CbnPzDyd/GwEPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}