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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4acdcbe33f98c5fe9aaa39fb095540d3f64ae47fb440bc8dd581be9a37002c05' 
  AND token = '6FJOmQiTV8jhWjRfW7laxxi+25rKotH4BXNLgC0Yoxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}