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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eaaf3fc816f1cc258191f9648af5b984b9933f9948e31b28370f2d1024965f9' 
  AND token = '877l2A53vVDVGVMrTjT2nNf7+id7y1rAUfy5kqnKCDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}