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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861d3a667df06f9487d4f6fde675bdeeb2cd64c49c972e2b618a9756163c4c8a' 
  AND token = 'B6X2mMtsKPmY5Fa9DhtDR2cJf1vbBOlnwrweRq26co4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}