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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ee805a22207f863d78d4c891feb3033acfed1fc0ab70b0ba8d31df9e603a8ad' 
  AND token = 'DxI3Io2dYe5b+8mm8FM5bZAV0DhQ42XKQ6xGA9cQ/10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}