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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee10d6e1ab1a0b73a757f728af3f76997ad143429b9f5a808193fdab880feb1f' 
  AND token = 'oeFzdjWHxn2BQ0wmUEOr/LFNHQ9SynHtd9PHRgjAguk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}