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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3d986b73ec5e75bc173f2a06b14b5d3031d6d807a912f69cef4d40e9dc4eac' 
  AND token = '44XJTfb3vNZHQc8ulNyqC0W4gzH5mvBrRsZnjg2Ux9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}