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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4477410da8b9a09e851788c63283a1917d712304737f61871a171f17e8c59ca1' 
  AND token = 'O2RFUcJVKGiQW0pLW3FCFbQSQm8C7nTdTe+LZUg9ERg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}