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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a07d29eefd089cef099184fa268aba7a47524b6d185ad110915e47990fa3611' 
  AND token = '0KBpy5h6NBPOTl46MSdO8jT0uq15aKJh2AVyuPZiK+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}