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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06dfa80d32f2eb0267bb1b77e670e21c82851709060fcf86e00a2a29ca7daec6' 
  AND token = 'B/35l5o9VsHEVNDAECz02/Q4DzAyT/ZxhKpbPre2aYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}