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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75366e0d03142e18e823cca2e863d83ebeb7c71fa130d76ebe5a11ff9723fabf' 
  AND token = 'NoIDAnqWyxLzsr7CXG4QWznm57izR8FkWWUetqltLs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}