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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea22032890a96534d72f31f7f37bbad8ab900fa15499dde9f9c06b8af23aa3b' 
  AND token = 'A1B26bbGxzXkFvBu1ojhhn3WAJ+Z9iGYExqE4Mv1CDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}